Recent publications
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Negative DNA supercoiling induces genome-wide Cas9 off-target activity
Molecular Cell, 2023
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Search and processing of Holliday junctions within long DNA by junction-resolving enzymes
Nature Communications, 2022
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A Minimal Load-and-Lock RuII Luminescent DNA Probe
Angewandte Chemie, 2021
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Cas12a target search and cleavage on force-stretched DNA
Physical Chemistry Chemical Physics, 2021
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A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules
Science advances, 2019
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DNA stretching induces Cas9 off-target activity
Nature Structure and Molecular Biology, 2019