Recent publications

  • Negative DNA supercoiling induces genome-wide Cas9 off-target activity

    Molecular Cell, 2023

  • Search and processing of Holliday junctions within long DNA by junction-resolving enzymes

    Nature Communications, 2022

  • A Minimal Load-and-Lock RuII Luminescent DNA Probe

    Angewandte Chemie, 2021

  • Cas12a target search and cleavage on force-stretched DNA

    Physical Chemistry Chemical Physics, 2021

  • A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules

    Science advances, 2019

  • DNA stretching induces Cas9 off-target activity

    Nature Structure and Molecular Biology, 2019